| Company: | Lupin Ltd. |
| Brand: | Bevazza 400mg Injection |
| Salt: | Bevacizumab |
| Innovator’s Name: | BevaciRel |
| Storage: | Store in a refrigerator (2 – 8°C). Do not freeze. |
| Strength: | 400mg |
| Dosage: | Injection |
Dosage form and Strength of Bevazza 400mg (Bevacizumab) Injection:
It is in Injection form.
Each 16ml vial contains Bevacizumab 400mg Concentrate solution for Intravenous (I.V) Infusion.
Mechanism of Action of Bevazza 400mg (Bevacizumab) Injection:
It is a monoclonal antibody that attaches to circulating Vascular Endothelial Growth Factor (VEGF) and inhibits angiogenesis, inducing cell death.
Inhibits VEGF binding to cell surface receptors, reducing microvascular growth of tumor blood vessels and limiting blood supply to tumor tissues.
Administration of Bevazza 400mg (Bevacizumab) Injection:
Use as Intravenous Infusion.
Single use vial.
Discard unused portion.
Do not self-medicate.
Use under medical supervision only.
Therapeutic Use of Bevazza 400mg (Bevacizumab) Injection:
Used with other chemotherapy medications to treat Metastatic Colorectal Cancer, Metastatic Renal Cell Carcinoma, Metastatic Cervical Cancer, Non-Squamous Lung Cancer, Epithelial Ovarian & Fallopian Tube Cancer, Hepatocellular Carcinoma, and Glioblastoma.
Usage Instruction of Bevazza 400mg (Bevacizumab) Injection:
Sterile, preservative-free solution for I.V. Infusion after dilution.
Single use vial.
Discard unused portion.
Do not self-medicate.
Take as directed by the Oncologist.
Keep out of reach of children.
Side Effects:
Rectal Bleeding, Muscle Weakness, Hypertension, Nosebleed, Decreased urine output, Dizziness, Change in taste, Headache, Dry Skin, Chest Pain, Heartburn, Weight loss, Sores in the mouth, Diarrhoea.
Safety Precautions:
Alcohol: Study unknown; consult doctor.
Pregnancy: Unsafe; may harm unborn baby. Consult doctor.
Lactating Mothers: Unsafe; consult doctor.
Driving: May affect ability; avoid driving. Consult doctor.
Renal Impairment: Generally safe; consult doctor for dosage adjustments.
Hepatic Impairment: Safe with precautions; consult doctor.
Contraindications: Known hypersensitivity, Bleeding disorder, Post-surgical patients.
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