| Company: | Novartis |
| Brand: | Arranon 250mg Injection |
| Salt: | Nelarabine |
| Innovator’s Name: | Atriance |
| Storage: | Store between 15°C to 30°C |
| Strength: | 250mg |
| Dosage: | Injection |
Dosage form and Strength of Arranon 250mg (Nelarabine) Injection:
Clear, colorless sterile solution for injection.
Each vial contains Nelarabine 250mg/50ml (5mg/ml) single dose vial.
Mechanism of Action:
Belongs to antimetabolites.
Transforms pro-drug into deoxyguanosine analogue 9-β-D-arabinofuranosylguanine (ara-G), a nucleoside metabolic inhibitor.
Kills cancer cells by interfering with DNA synthesis.
Administration:
Intravenous infusion.
Do not self-medicate.
Use under medical supervision only.
Therapeutic Use:
Treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL).
Usage Instruction:
Intravenous infusion.
Single use vial.
Do not use if solution is cloudy or contains precipitate.
Discard unused portion.
Use under medical supervision only.
Side Effects:
Nausea, Vomiting, Constipation, Headache, Cough, Diarrhoea, Dizziness, Drowsiness, Tiredness, Loss of appetite.
Safety Precautions:
Alcohol: Study unknown; consult doctor.
Pregnancy: Unsafe; may harm unborn baby; consult doctor.
Lactating Mothers: Study unknown; consult doctor.
Driving: May affect driving; consult doctor.
Renal Impairment: Use with caution; consult doctor.
Hepatic Impairment: Use with caution; consult doctor.
Contraindications: Known hypersensitivity.
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